pde4 inhibitors Search Results


purified pde4d  (Pfizer Inc)
90
Pfizer Inc purified pde4d
Purified Pde4d, supplied by Pfizer Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/purified pde4d/product/Pfizer Inc
Average 90 stars, based on 1 article reviews
purified pde4d - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
's potent pde5 inhibitor e1  (Eisai Inc)
90
Eisai Inc 's potent pde5 inhibitor e1
's Potent Pde5 Inhibitor E1, supplied by Eisai Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/'s potent pde5 inhibitor e1/product/Eisai Inc
Average 90 stars, based on 1 article reviews
's potent pde5 inhibitor e1 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
type 4 phosphodiesterase (pde4) inhibitors  (Brookhaven Instruments)
90
Brookhaven Instruments type 4 phosphodiesterase (pde4) inhibitors
Type 4 Phosphodiesterase (Pde4) Inhibitors, supplied by Brookhaven Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/type 4 phosphodiesterase (pde4) inhibitors/product/Brookhaven Instruments
Average 90 stars, based on 1 article reviews
type 4 phosphodiesterase (pde4) inhibitors - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
topical pde-4 inhibitors  (Anacor Pharmaceuticals)
90
Anacor Pharmaceuticals topical pde-4 inhibitors
Topical Pde 4 Inhibitors, supplied by Anacor Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/topical pde-4 inhibitors/product/Anacor Pharmaceuticals
Average 90 stars, based on 1 article reviews
topical pde-4 inhibitors - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
rolipram (c 16 h 21 3  (Biomol GmbH)
90
Biomol GmbH rolipram (c 16 h 21 3
Rolipram (C 16 H 21 3, supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rolipram (c 16 h 21 3/product/Biomol GmbH
Average 90 stars, based on 1 article reviews
rolipram (c 16 h 21 3 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
pde4-specific inhibitor etazolate  (ApexBio)
90
ApexBio pde4-specific inhibitor etazolate
Pde4 Specific Inhibitor Etazolate, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pde4-specific inhibitor etazolate/product/ApexBio
Average 90 stars, based on 1 article reviews
pde4-specific inhibitor etazolate - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
selective pde4 inhibitors  (Inserm Transfert)
90
Inserm Transfert selective pde4 inhibitors
Selective Pde4 Inhibitors, supplied by Inserm Transfert, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/selective pde4 inhibitors/product/Inserm Transfert
Average 90 stars, based on 1 article reviews
selective pde4 inhibitors - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
oral pde4 inhibitors  (Abbott Laboratories)
90
Abbott Laboratories oral pde4 inhibitors
Oral Pde4 Inhibitors, supplied by Abbott Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/oral pde4 inhibitors/product/Abbott Laboratories
Average 90 stars, based on 1 article reviews
oral pde4 inhibitors - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
inhaled phosphodiesterase (pde) 4 inhibitors  (Nycomed)
90
Nycomed inhaled phosphodiesterase (pde) 4 inhibitors
Inhaled Phosphodiesterase (Pde) 4 Inhibitors, supplied by Nycomed, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/inhaled phosphodiesterase (pde) 4 inhibitors/product/Nycomed
Average 90 stars, based on 1 article reviews
inhaled phosphodiesterase (pde) 4 inhibitors - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
pde4 inhibitors  (Plexxikon)
90
Plexxikon pde4 inhibitors
Pde4 Inhibitors, supplied by Plexxikon, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pde4 inhibitors/product/Plexxikon
Average 90 stars, based on 1 article reviews
pde4 inhibitors - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
pde4 activity assay kit  (Promega)
90
Promega pde4 activity assay kit
A–C. The chemical structure of Forsythin extracted from Forsythia suspensa seeds. Forsythin is an o-linked β-D-glucopyranosylated lignin that can be hydrolyzed (Red line). D. Predicted docking site of Forsythin with <t>PDE4.</t> E. Predicted residue electrostatic and van der Waals interactions between PDE4 amino acids and Forsythin. Using ZINCPharmer , a pharmacophore model was generated (upper left) and used to screen the lead compounds from an 18.3 million purchasable compound library.
Pde4 Activity Assay Kit, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pde4 activity assay kit/product/Promega
Average 90 stars, based on 1 article reviews
pde4 activity assay kit - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
topical pde-4 inhibitor  (Tokyo Chemical Industry)
90
Tokyo Chemical Industry topical pde-4 inhibitor
Summary of published (MEDLINE, EMBASE, congress abstract search, as of 11 January 2024) phase III and IV clinical trials on biologic drugs in AD treatment. Phase III and IV studies without published results are not included.
Topical Pde 4 Inhibitor, supplied by Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/topical pde-4 inhibitor/product/Tokyo Chemical Industry
Average 90 stars, based on 1 article reviews
topical pde-4 inhibitor - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


A–C. The chemical structure of Forsythin extracted from Forsythia suspensa seeds. Forsythin is an o-linked β-D-glucopyranosylated lignin that can be hydrolyzed (Red line). D. Predicted docking site of Forsythin with PDE4. E. Predicted residue electrostatic and van der Waals interactions between PDE4 amino acids and Forsythin. Using ZINCPharmer , a pharmacophore model was generated (upper left) and used to screen the lead compounds from an 18.3 million purchasable compound library.

Journal: PLoS ONE

Article Title: Novel PDE4 Inhibitors Derived from Chinese Medicine Forsythia

doi: 10.1371/journal.pone.0115937

Figure Lengend Snippet: A–C. The chemical structure of Forsythin extracted from Forsythia suspensa seeds. Forsythin is an o-linked β-D-glucopyranosylated lignin that can be hydrolyzed (Red line). D. Predicted docking site of Forsythin with PDE4. E. Predicted residue electrostatic and van der Waals interactions between PDE4 amino acids and Forsythin. Using ZINCPharmer , a pharmacophore model was generated (upper left) and used to screen the lead compounds from an 18.3 million purchasable compound library.

Article Snippet: PDE4 activity assay kit was from Promega.

Techniques: Residue, Generated, Drug discovery

For the PDE activity assay, all test compounds were diluted in DMSO with final concentrations in each assay of 100, 10, 1, 0.1, 0.01, 0.001, 0.0001 µM. For the PDE4 activity assay, 10 mU of purified PDE4 (Millipore) was used per reaction. Compounds 6, 7, 9 and 13 (blue underline) were further tested in PDE3, 5, 7, 10 activity assays in which 25 mU of purified enzyme was used per reaction. Summary of compound IC 50 in lower right corner.

Journal: PLoS ONE

Article Title: Novel PDE4 Inhibitors Derived from Chinese Medicine Forsythia

doi: 10.1371/journal.pone.0115937

Figure Lengend Snippet: For the PDE activity assay, all test compounds were diluted in DMSO with final concentrations in each assay of 100, 10, 1, 0.1, 0.01, 0.001, 0.0001 µM. For the PDE4 activity assay, 10 mU of purified PDE4 (Millipore) was used per reaction. Compounds 6, 7, 9 and 13 (blue underline) were further tested in PDE3, 5, 7, 10 activity assays in which 25 mU of purified enzyme was used per reaction. Summary of compound IC 50 in lower right corner.

Article Snippet: PDE4 activity assay kit was from Promega.

Techniques: Activity Assay, Purification

Summary of published (MEDLINE, EMBASE, congress abstract search, as of 11 January 2024) phase III and IV clinical trials on biologic drugs in AD treatment. Phase III and IV studies without published results are not included.

Journal: Journal of Clinical Medicine

Article Title: A Comprehensive Review of Biologics in Phase III and IV Clinical Trials for Atopic Dermatitis

doi: 10.3390/jcm13144001

Figure Lengend Snippet: Summary of published (MEDLINE, EMBASE, congress abstract search, as of 11 January 2024) phase III and IV clinical trials on biologic drugs in AD treatment. Phase III and IV studies without published results are not included.

Article Snippet: NCT04250350 (ADore) , Phase III , 206; Adolescents (≥12 to <18 years old, weighing ≥ 40 kg) , Lebrikizumab 250 mg Q2W through week 52 TCS, TCI, topical PDE-4 inhibitor allowed as rescue treatment. , Week 16 results: IGA 0-1: Lebrikizumab 250 mg Q2W (46.3%) EASI-75: Lebrikizumab 250 mg Q2W (73.2%) Week 52 results: IGA 0-1: Lebrikizumab 250 mg Q2W (62.6%) EASI-75: Lebrikizumab 250 mg Q2W (81.9%) , [ ] .

Techniques: Clinical Proteomics, Vaccines, Selection, Medications